双因素判别分析胃癌组织与正常组织自体荧光光谱     

马君  史晓凤  李颖  王荣  毛伟征  郑荣儿  孟继武 《中国海洋大学学报(自然科学版)》2004,34(4):662-666

通过对手术切除的37例胃癌患者的离体标本的自体荧光光谱检测,显示308nm,337nm激发光谱均呈双主峰结构,双主峰的比值均能区分胃癌与正常胃壁(P<0.001).分别用308nm,337nm激发荧光光谱单因素分析诊断胃癌的灵敏度、特异度、阳性预测值分别为88.8%,86.8%,86.4%和80.1%,72.1%,67.5%.对308nm及337nm激发荧光光谱双因素分析,癌诊断的灵敏度、特异度、阳性预测值分别为94.4%,92.1%,91.9%,其诊断正确符合率明显高于单因素分析的结果.研究表明,以308nm及337nm双波长激发检测胃壁浆膜,双因素判别算法可较好地区分胃癌,这种方法有望成为手术中快速识别胃癌在胃壁的浸润范围的有效方法.  相似文献   

Elements pollution in the extremely high tumor risk residents in Chaoshan littoral, southern China     

Min SU Min LIU Dongping TIAN Guohong ZHANG Liangli HONG Yuxia GAO 《中国地球化学学报》2006,25(B08):61-61

Background ＆ aim： To investigate and analyze the elements pollution in the extremely high tumor risks residents in the Chaoshan littoral, southern China. Methods： 19 elements including Cr, Mn, Ni, Sr, Pb, Zn, Co, Sn, Th, Tl, Se, Hg, Cu, Mo, Cd, Sb, U, Ge, As, and Al were measured from 145 hair samples of residents from the high-risk Nanao Island （mortality of cancer 173-156/106 in recent 30 years）, Shantou high-risk village （mortality of cancer 230.4/106 in recent three years）, and two controls Shanwei （mortality of cancer 32/106 in 1970s） and Meizhou Hakka （incidence of cancer 103/106 ） using AAS, AFS, ICP-MS methods collaborated with Beijing University. And 21 samples of water, 18 samples office from the Nanao Island, Shantou high-risk village, and other low-risk controls were measured using the same methods. Results： The element analysis showed that levels of CD, PB in the Shantou high-risk village were the highest, Hg, MN, SR, SB, TH, U on the Nanao Island were the highest in hairs. Conclusions： It is indicated that there occurred elements pollution among the local high-risk population.  相似文献   

肝硬化再生结节病的CT诊断与鉴别   总被引：1，自引：1，他引：1  

黄绍权 《CT理论与应用研究》2002,11(1):34-35

本文目的是探讨肝硬化再生结节的CT诊断及鉴别，提高肝内结节的诊断水平。方法：对120例肝硬化再生结节的CT平扫及增强图象的分析。结果：肝硬化再生结节以圆形为主，直径在5mm－55mm之间，平扫多数呈高密度，结节的分布据结节的分型而定。结论：明确肝硬化再生结节的CT诊断依据及与肝癌、肝血管瘤的鉴别。  相似文献   

Radon,Lung Cancer Risk and Environmental Geology in Gejiu Area     

卢伟  王任重等 《中国地球化学学报》1997,16(3):278-282

The incidence of lung cancer in the Gejiu area of Yunnan Province ranks the first in the world.The radon level(indoor,soil) was measured in the Gejiu area by the SSNTD method from 1990 to 1996,The result indicates an extensive high-level of indoor radon in that area though U and Th are lower in local limestones,The indoor radon level of houses located in the geologic fault zone is 6 times high that 2km far from the fault zone.The reason probably is that the radon level of soil in the fault is 6-8 times high that 1 km far from the faults.our data indicate that a lower range of radon levels,0-100Bq.m^-3,exists in healthy families.However,a higher radon level,over 800 Bq.m^-3,is often found corresponding to that of cancer patients‘ homes(the house-owners are suffering from either lung cancer or leukaemia or liver cancer),Obviously,an increase in lung cancer incidence follows an increase in indoor radon level,The risk of cancer induced by indoor radon is no longer an inference,but a fact.  相似文献   

外围性小肺癌的CT诊断     

唐桂长  房桂云 《CT理论与应用研究》1994,3(3):36-41

作者报告了４０例外围性小肺癌。并对≤３ｃｍ的外围性小肺癌的ＣＴ征象进行了讨论和总结。作者认为：小结节征、分叶征、棘状突、空泡征、胸膜凹陷等征象，对外围性小肺癌有诊断价值。  相似文献   

Modelling and predicting the spatial dispersion of skin cancer considering environmental and socio-economic factors using a digital earth approach     

Zohreh Masoumi  John L. van Genderen  Mohammad Sadi Mesgari 《International Journal of Digital Earth》2020,13(6):661-682

ABSTRACT

Almost all causative factors of diseases depend on location. The Digital Earth approach is suitable for studying diseases globally. Geospatial information systems integrated with statistical models can be used to model the relationship between a disease and its causative factors. Through modelling, the most important causative factors can be extracted and the epidemiology of the disease can be observed. In this paper, skin cancer (the most common type of cancer) has been modelled based on its causative factors, including climate factors, people's occupations, nutrition habits, socio-economic factors, and usage of chemical fertiliser. To fit the model, a data framework was first designed, and then data were gathered and processed. Finally, the disease was modelled using Generalised Linear Models (GLM), a statistical model based on the location of the factors. The results of this study identify the most important causative factors together with their relative priority. Furthermore, a model was used to predict the change in skin cancer occurrences caused by a change in one of its causative factors. This work illustrates the ability of the model to predict disease occurrence. Thus, by using this Digital Earth approach, skincancer can be studied in all the key countries around the world.  相似文献   

开放式低场磁共振诊断直肠癌新方法征像分析     

钟洪波  李晓阳  李骥 《CT理论与应用研究》2007,16(4):66-69

目的:探讨开放式低场磁共振诊断直肠癌的扫描方法并对所见征像进行分析.资料与方法:搜集我院病理证实的直肠癌患者16例.16例患者能够配合整个扫描过程,无严重心、肝、肺、肾疾病.扫描前1天患者做肠道准备,扫描前15分钟注射解痉剂,经肛门插管注入生理盐水1000ml左右,然后注入气体1000ml左右,尽量使肠管扩张,患者如有不适,应立即停止灌肠.检查前对患者进行呼吸训练,使患者平静呼吸,呼吸幅度尽量减小.分别采用仰卧位与俯卧位进行检查.结果直肠癌肿MRI主要表现为直肠局限性或弥漫性肠壁增厚和肿块形成.T1癌肿表现为中等偏低信号,边界清楚.T2癌肿呈较高信号.Gd-DTPA增强技术,癌肿显示不规则强化.对周围脏器如子宫、膀胱、前列腺和盆腔壁等显示良好.结论:开放式低场磁共振扫描仪在诊断直肠癌过程中,操作相对简单,患者痛苦小,容易配合,病变显示清晰.  相似文献   

阳和汤联合唑来膦酸治疗阳虚寒凝型乳腺癌骨转移30例          下载免费PDF全文

冯磊  李玲  李阳 《应用海洋学学报》2022,38(10):12

目的：观察阳和汤联合唑来膦酸治疗阳虚寒凝型乳腺癌骨转移的临床疗效及安全性。方法：将60 例阳虚寒凝型乳腺癌骨转移患者随机分为治疗组和对照组,每组各30 例。对照组给予唑来膦酸注射液治疗,治疗组在对照组基础上加用阳和汤治疗。观察2组的癌痛疗效、生活质量、数字分级法（NRS）评分、中医证候积分、骨代谢指标［血钙、血清骨代谢标志物碱性磷酸酶（ALP）、I型胶原N末端肽（NTX）水平］以及不良反应。结果：骨转移癌痛总有效率治疗组为73.4%（22/30）,对照组为60.0%（18/30）;生活质量总有效率治疗组为86.7%（26/30）,对照组为73.3%（22/30）,2组比较,差异均有统计学意义（P<0.05）。治疗组NRS评分、中医证候积分治疗前后组内比较及治疗后与对照组比较,2组ALP、NTX水平治疗前后组内比较及治疗后组间比较,差异均有统计学意义（P<0.05或P<0.01）。2组血钙水平、不良反应发生率比较,差异均无统计学意义（P>0.05）。结论：阳和汤可以作为阳虚寒凝型乳腺癌骨转移患者的辅助治疗手段,值得临床推广应用。  相似文献   

基于数据挖掘分析中药复方治疗肺癌伴恶性胸腔积液的用药规律          下载免费PDF全文

关鹏  沈云博  刘枫 《应用海洋学学报》2022,38(10):34

目的：运用中医传承计算平台（V3.0）分析中医药治疗肺癌伴恶性胸腔积液的用药规律。方法：计算机检索2000年1月1日至2022年2月28日中国知网（CNKI）、万方数据（WANFANG DATA）、维普中文科技期刊数据库（VIP）中关于中药复方治疗肺癌伴恶性胸腔积液的文献,分析中药的性味归经、功效、频次、药物组合、关联规则及聚类等。结果：共纳入文献98篇,处方103首,中药197味。频次≥20次的中药有18味,排前10位的依次为葶苈子、茯苓、白术、黄芪、大枣、甘草、泽泻、桂枝、半夏、薏苡仁。四气以寒、温、平为主;五味以甘、苦、辛为主;归经以肺、脾、胃经为主。排前3位的功效依次为补虚、利水渗湿、化痰止咳平喘。用药频次≥20次的中药组合有37组,排前4位的依次为茯苓-葶苈子、白术-茯苓、茯苓-黄芪、大枣-葶苈子。支持度≥25%的核心药物为黄芪、白术、茯苓、甘草、葶苈子、大枣、桂枝、泽泻。中药聚类分析提取到4个核心组合。结论：肺癌伴恶性胸腔积液多属晚期,以气血阴阳俱虚为本,饮停胸胁为标,病机多虚实夹杂。中医药治疗此病多以甘温益气补虚治本,苦寒泻肺利水治标,同时兼以温阳化气。  相似文献   

Esophageal cancer spatial and correlation analyses：Water pollution,mortality rates,and safe buffer distances in China     

ZHANG Xueyan  ZHUANG Dafang  MA Xin  JIANG Dong 《地理学报》2014,24(1):46-58

Esophageal cancer exhibits one of the highest incidence and mortality rates in China. Malignant tumors caused by esophageal cancer, and the relationship to environmental factors has been the focus of many public health studies. This study applied spatial analysis to ascertain the relationship between water pollution and esophageal cancer mortality rates nationwide. We employed two datasets, including a national investigation of esophageal cancer rates and distribution, and national water quality grades in China's primary rivers and lakes. Esophageal cancer data were grouped based on different water quality grades, which included a scaled buffer distance from rivers and lakes. Non-parametric correlation analyses were performed to examine the presence or absence of the following correlations: (i) esophageal cancer mortality and buffer distance from rivers and lakes; and (ii) esophageal cancer mortality and water quality grade values. The present study revealed a significant positive correlation between widespread water pollution and esophageal cancer mortality nationwide; and a significant negative correlation between esophageal cancer mortality, and buffer distance from rivers and lakes.  相似文献